Versantis, a pharmaceutical company focused on the development of products addressing a high unmet medical need in the diagnosis, prevention, and treatment of liver diseases, has closed a Series A financing round of 4,4 Mio.CFH. Redalpine Venture Partners led the round and was joined by Altus Partners, HealthEquity, Occident Group, Zürcher Kantonalbank, and private investors.

The proceeds will be used to progress the lead candidate, VS-01, into a Phase I/II clinical trial targeting hepatic encephalopathy in acute on chronic-liver-failure, as well as to further develop the company’s preclinical pipeline.

“This is an exciting time for Versantis as we advance the development of our lead compound VS-01 to reach Phase IIa and deliver proof-of-safety and preliminary proof-of-efficacy in the clinic; this will represent a major milestone which will serve as a common basis for 3 different indications in acute liver failure.” said Dr. Meriam Kabbaj, COO and co-founder of Versantis.

120.000 patients yearly in the EU and USA

Acute-on-Chronic Liver Failure (ACLF) and Acute Liver Failure (ALF) are rare diseases characterized by an acute decompensation of the liver supplemented by hepatic encephalopathy, a neuropsychiatric condition rapidly progressing into coma and death. These indications represent about 120.000 patients yearly in the EU and USA and continue to increase due to the aging population, and a higher prevalence of diabetes, obesity, alcohol, and drug intoxications. Pediatric patients suffering from congenital Urea Cycle Disorders (UCD) represent a third indication for VS-01 which has the potential to be the first tailored lifesaving therapy meeting the specific needs of this population.